Investigation of glycation products by THz time-domain spectroscopy

O. Cherkasova, M. Nazarov, Y. Kistenev, A. Shkurinov, A. Borisov, E. E. Ilyasova, A. Knyazkova
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引用次数: 1

Abstract

Glycation is the non-enzymatic reaction between reducing sugars, such as glucose, and proteins, lipids or nucleic acids. This process involvement in various pathologies of the human body, including diabetes and aging, and is an intensive field of research. Terahertz time-domain spectroscopy (THz-TDS) has been used for assay of glycation products. The transmission and the attenuated total internal reflection geometries have been used for measuring of a number glycation products in aqueous solutions at 0.2-2.5 THz.
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太赫兹时域光谱法研究糖基化产物
糖基化是还原糖(如葡萄糖)与蛋白质、脂质或核酸之间的非酶促反应。这一过程涉及人体的各种病理,包括糖尿病和衰老,是一个密集的研究领域。太赫兹时域光谱(THz-TDS)已被用于糖基化产物的测定。透射和衰减的总内反射几何形状已被用于测量0.2-2.5太赫兹水溶液中的一些糖基化产物。
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