Combined Retrospective-Prospective Cohort Study to Know the Risk of Sensorineural Hearing Loss in Patients of Drug Resistant TB Receiving Anti Tuberculous Treatment (ATT) at Tertiary Care Centre in South Gujarat.

IF 9.1 1区农林科学 Q1 PLANT SCIENCES Annual review of phytopathology Pub Date : 2023-12-01 Epub Date: 2023-06-15 DOI:10.1007/s12070-023-03702-8

Khushi N Bhavsar, Anandkumar V Chaudhari, Jahanvika M Chauhan, Rahulkumar B Patel, Jaymin A Contractor, Khyati D Shamaliya, Pururava J Desai, Prachi P Roy, Hiteshri C Patel

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Abstract

Combined retrospective-prospective cohort study was done to know the risk of sensorineural hearing loss in patients of drug resistant Tuberculosis (TB) receiving Anti Tuberculous Treatment (ATT) at tertiary care centre in South Gujarat. Study was done by using retrospective and prospective data of the patients of drug resistant TB of NCHS who received injectable ATT and referred by department of Respiratory Medicine to ENT department for purpose of hearing evaluation pre and post treatment (Case cohort). Age and sex matched control cohort was also used which includes patients of non-drug resistant TB who were not receiving Injectable ATT. Incidence of SNHL in patients taking ATT for drug resistant tuberculosis in our study was 33.9%. The Relative Risk of SNHL was 14.3%. The Attributable Risk of SNHL (preventable SNHL) was 93%.

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南古吉拉特邦三级医疗中心接受抗结核治疗(ATT)的耐药结核病患者感音神经性听力损失风险的回顾性-前瞻性联合队列研究

在南古吉拉特邦三级保健中心进行了回顾性-前瞻性联合队列研究，以了解接受抗结核治疗(ATT)的耐药结核病(TB)患者感音神经性听力损失的风险。本研究采用NCHS耐药结核病患者的回顾性和前瞻性资料，这些患者接受注射ATT治疗，并由呼吸内科转诊至耳鼻喉科进行治疗前后听力评估(病例队列)。年龄和性别匹配的对照队列包括未接受注射ATT治疗的非耐药结核病患者。在我们的研究中，因耐药结核病而接受ATT治疗的患者SNHL发病率为33.9%。SNHL的相对危险度为14.3%。SNHL(可预防SNHL)的归因风险为93%。

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来源期刊

Annual review of phytopathology 生物-植物科学

CiteScore

16.60

自引率

1.00%

发文量

期刊介绍： The Annual Review of Phytopathology, established in 1963, covers major advancements in plant pathology, including plant disease diagnosis, pathogens, host-pathogen Interactions, epidemiology and ecology, breeding for resistance and plant disease management, and includes a special section on the development of concepts. The journal is now open access through Annual Reviews' Subscribe to Open program, with articles published under a CC BY license.