Anaplastic thyroid cancer: current capabilities of an oncologist

A. Pylev, D. Romanov, N. Lasunin, D. A. Balaeva, M. P. Kazakov
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Abstract

Continuous development of oncology as a science in the last decades and years led to noticeable improvement in treatment outcomes for patients with various malignant tumors. Diagnostics, surgery, radiotherapy significantly contributed to this improvement, however they cannot be compared to the progress achieved through advancements in our knowledge of genetic structure of tumors and subsequent advancements in pharmacology which allowed to achieve qualitatively better survival in oncological patients. These advancements did not leave out such a serious and highly lethal, though fortunately rare, disease as anaplastic thyroid cancer. This article is dedicated to the possibilities of using checkpoint inhibitors in treatment of this pathology to increase expected life span of the patients.
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间变性甲状腺癌:肿瘤学家的当前能力
近几十年来肿瘤学作为一门科学的不断发展,使各种恶性肿瘤患者的治疗效果显著改善。诊断、手术、放射治疗对这一进步做出了重大贡献,然而,它们无法与我们对肿瘤遗传结构的知识的进步和随后药理学的进步所取得的进步相比,药理学的进步使肿瘤患者的生存质量得到了提高。这些进步并没有忽略像间变性甲状腺癌这样严重和高度致命的疾病,尽管幸运的是罕见的。本文致力于使用检查点抑制剂治疗这种病理的可能性,以增加患者的预期寿命。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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