Effects of blood pressure, blood cholesterol and smoking on the functional capacity of post myocardial infarction patients in the early stages of cardiac rehabilitation

D.A. Brodie , X. Liu , P.E. Bundred
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Abstract

The purpose of the study was to examine the contribution of blood pressure, blood cholesterol and smoking on the functional capacity of post myocardial infarction patients (PMIP) during exercise. Forty six male non-blockade recent PMIP were measured for systolic blood pressure (SBP) and blood cholesterol (BC), and were also asked about personal smoking status. The subjects all performed a graded exercise test (modified Bruce protocol) on a motorized treadmill, during which time ratings of perceived exertion and blood pressure were measured every 3 min, oxygen uptake (VO2) and heart rate (HR) were measured every 30s and a 12-lead electrocardiogram was recorded continuously. Metabolic equivalents (METs) were derived from VO2and the patients’ risk factors for coronary heart disease were obtained using the coronary risk-disc and expressed as Dundee Rank (DR). The results produced a multiple regression of SBP, BC and smoking with exercise time of r = 0.76 and with METs of r = 0.73 which were very similar to the values using DR alone. A DR value of 71 and above was equivalent to a MET value of 7.5 which is often used as the criterion for considering a patient to be at ‘low risk’ during cardiac rehabilitation. This means that the Dundee Risk-Disc may have a place in assisting the health professional to establish which patients should be capable of achieving the 7.5 MET threshold. This could be useful in giving special attention to those patients who are underperforming. The poor correlation between RPE and VO2recognises individual differences and demonstrates the need for each patient to establish their own RPE/work relationship.

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血压、血胆固醇和吸烟对心肌梗死后患者心脏康复早期功能的影响
本研究的目的是研究血压、血胆固醇和吸烟对心肌梗死后患者(PMIP)运动期间功能的影响。我们测量了46名男性近期非阻断性PMIP患者的收缩压(SBP)和血胆固醇(BC),并询问了他们的个人吸烟状况。所有受试者均在电动跑步机上进行分级运动测试(改良布鲁斯方案),在此期间,每3分钟测量一次感知运动评分和血压,每30秒测量一次摄氧量(VO2)和心率(HR),并连续记录12导联心电图。通过vo2计算代谢当量(METs),通过冠状动脉风险盘计算患者冠心病危险因素,用邓迪秩(Dundee Rank, DR)表示。结果产生了收缩压、BC和吸烟的多元回归,运动时间r = 0.76,代谢当量r = 0.73,这与单独使用DR的值非常相似。DR值为71及以上相当于MET值为7.5,MET值通常被用作考虑患者在心脏康复期间处于“低风险”的标准。这意味着邓迪风险盘可能在帮助卫生专业人员确定哪些患者应该能够达到7.5 MET阈值方面发挥作用。这对于给予那些表现不佳的病人特别关注是有用的。RPE和vo2之间的低相关性认识到个体差异,并表明每个患者需要建立自己的RPE/工作关系。
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