Crystal engineering in the development of improved pesticide products

Advanced Agrochem Pub Date : 2022-09-01 DOI:10.1016/j.aac.2022.09.001

Xiaofang Niu, Rui Yang, Huimin Zhang, Jingxiang Yang

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引用次数: 5

Abstract

Pesticides might be the only group of poisonous chemicals that are widely sprayed into the environment, but the use of pesticides is inevitable for crop protection and infectious disease control. When an ideal new pesticide compound is selected, its properties must be optimized to realize the full potential of the compound and extend its lifespan in the market. Crystal engineering has proven to be a viable strategy for manipulating the properties of solid-state pesticides. This review describes basic concepts of crystal engineering and its application in pesticide development through representative cases reported mainly by large agrochemical companies. The solid forms that present improved properties could justify patent protection, extending the market exclusivity of the pesticide product. The purpose of this review is to present the potential impact of crystal engineering strategies on the improvement of pesticide products, with emphasis on the importance of comprehensive characterization of the crystallization behaviors of a selected pesticide during its entire life cycle.

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晶体工程在改良农药产品开发中的应用

农药可能是唯一一组被广泛喷洒到环境中的有毒化学物质，但为了保护作物和控制传染病，使用农药是不可避免的。当选择一种理想的新农药化合物时，必须对其性能进行优化，以充分发挥该化合物的潜力，延长其在市场上的使用寿命。晶体工程已被证明是一种可行的策略来操纵固态农药的性质。本文通过以大型农化企业为代表的典型案例，阐述了晶体工程的基本概念及其在农药开发中的应用。表现出改进性能的固体形式可以证明专利保护的合理性，扩大农药产品的市场独占性。这篇综述的目的是介绍晶体工程策略对农药产品改进的潜在影响，重点是综合表征选定农药在其整个生命周期中的结晶行为的重要性。

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来源期刊

Advanced Agrochem

CiteScore

3.50

自引率

0.00%

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