Defining a Functional Centromere

N. Eckardt
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引用次数: 1

Abstract

The question of what makes a functional centromere remains one of the most important and intriguing unanswered questions in biology. The centromere boundary can be defined by identifying sequences that bind to CENH3, a centromere-specific histone H3 variant (called CENP-A in mammals; reviewed in [
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定义功能性着丝粒
是什么构成了一个功能性的着丝粒,这个问题仍然是生物学中最重要和最有趣的未解之谜之一。着丝粒边界可以通过识别与CENH3结合的序列来定义,CENH3是一种着丝粒特异性组蛋白H3变体(在哺乳动物中称为CENP-A;在[
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