Troponina i en preeclampsia y eclampsia

Abstract

Objective

To compare serum troponin i concentrations in eclamptic patients, preeclamptic patients, and normotensive pregnant women.

Materials and method

We included 30 patients with mild preeclampsia (group A), 30 patients with severe preeclampsia (group B), and 30 patients with eclampsia (group C). A control group was selected with a similar age and body mass index to the study groups and consisted of 30 healthy normotensive pregnant women (group D). Only nulliparous women were included. Serum samples were collected from all patients before delivery and in the study groups immediately after diagnosis for troponin i determination.

Results

Serum troponin i values were higher in eclamptic patients (0.171 ± 0.025 ng/mL) and in severe preeclamptic patients (0.168 ± 0.024 ng/mL) and were lower in mild preeclamptic patients (0.123 ± 0.015 ng/mL). Serum troponin i values were significantly higher in the study groups than in the control group (0.049 ± 0.034 ng/mL; P < .0001). Linear regression analysis revealed that the factors significantly related to serum troponin i concentrations were 24-hour proteinuria and creatinine (P < .05).

Conclusion

Tropinin i concentrations were higher in eclamptic and preeclamptic patients than in healthy normotensive pregnant women without these complications.