{"title":"Regeneron Looks to Avalanche’s Ocular BioFactory™ for Potential Eylea® Successor","authors":"Heather Cartwright","doi":"10.3833/PDR.V2014I6.2036","DOIUrl":null,"url":null,"abstract":"In order to strengthen its ophthalmology pipeline and defend its Eylea® (aflibercept) franchise in the long term, Regeneron Pharmaceuticals has partnered with Avalanche Biotechnologies to develop and commercialise next-generation gene therapies for ophthalmologic diseases using Avalanche’s adeno-associated virus (AAV)-based Ocular BioFactory™ platform. The collaboration covers up to eight different targets and provides Regeneron with a time-limited right of first negotiation for certain rights to Avalanche’s lead asset AVA-101, which is in Phase IIa development for wet age-related macular degeneration.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"81 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2014-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmadeals Review","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3833/PDR.V2014I6.2036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In order to strengthen its ophthalmology pipeline and defend its Eylea® (aflibercept) franchise in the long term, Regeneron Pharmaceuticals has partnered with Avalanche Biotechnologies to develop and commercialise next-generation gene therapies for ophthalmologic diseases using Avalanche’s adeno-associated virus (AAV)-based Ocular BioFactory™ platform. The collaboration covers up to eight different targets and provides Regeneron with a time-limited right of first negotiation for certain rights to Avalanche’s lead asset AVA-101, which is in Phase IIa development for wet age-related macular degeneration.
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