The relation between leptin and osteocalcin and various anthropometric measures in preterm and full-term babies.

N. Amr, Salwa Elbatrawy, S. Atef, Rasha F. Darwish, Adham Hegazy
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引用次数: 1

Abstract

Leptin plays a role in foetal growth. Osteocalcin, a bone specific protein, reflects bone formation rate. This study aims to investigate the effect of leptin and osteocalcin on physical growth of newborns. About 40 full-term and 41 preterm healthy babies were included. Umbilical cord samples were analysed for leptin and osteocalcin. Anthropometric measurements were taken on newborns. Leptin was significantly higher in full terms compared to preterms with no significant difference in osteocalcin. A significant positive correlation existed between leptin and anthropometric measurements in both groups. Osteocalcin was positively correlated in full terms and negatively correlated in preterms with most measurements. A positive correlation between leptin and osteocalcin was found in full terms only. The study documented the association of leptin and osteocalcin with physical growth of full-term babies. This was true regarding leptin in preterms, but not osteocalcin which could be explained by excess bone turnover in preterms.
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早产儿和足月儿瘦素和骨钙素与各种人体测量指标的关系。
瘦素在胎儿生长中起着重要作用。骨钙素是一种骨特异性蛋白,反映骨形成速率。本研究旨在探讨瘦素和骨钙素对新生儿身体发育的影响。约有40名足月健康婴儿和41名早产儿被纳入研究。分析脐带样品中瘦素和骨钙素的含量。对新生儿进行人体测量。足月瘦素明显高于早产儿,而骨钙素无显著差异。在两组中,瘦素与人体测量值之间存在显著的正相关。骨钙素与大多数测量值在足期呈正相关,在早产期呈负相关。瘦素和骨钙素之间存在正相关关系。该研究记录了瘦素和骨钙素与足月婴儿身体发育的关系。对于早产儿的瘦素来说,这是正确的,但对于骨钙素来说,这可以用早产儿过度的骨转换来解释。
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