Antibacterial activities of triterpenes from leaves of Cissus incisa

Deyani Nocedo-Mena, E. Garza, Mauricio González-Ferrara, M. D. R. Camacho-Corona
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Abstract

Terpenoids play a crucial role in the performance of diverse ecological functions in response to biotic and abiotic factors. They are classified as secondary metabolism products. Among their functions are: be pollinating attractants, herbivore deterrents, insecticides / repellents, antibacterial compounds. Like many other natural products, they show biological activities, which have been exploited in the prevention and treatment of human diseases. As part of the phytochemical study performed on the Cissus incisa specie, the characterization using GC/MS of a triterpenes mixture of the chloroform / methanol 1:1 extract was carried out. In addition, the antibacterial activity was evaluated against nine strains of multi-resistant clinical isolates. As a result, C. incisa can be considered for further investigations as a source of compounds with antibacterial properties
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茜草叶片三萜的抑菌活性研究
萜类化合物在响应生物和非生物因子的多种生态功能中起着至关重要的作用。它们被归类为次级代谢产物。它们的功能包括:授粉引诱剂、食草动物驱避剂、杀虫剂/驱避剂、抗菌化合物。与许多其他天然产物一样,它们具有生物活性,已被用于预防和治疗人类疾病。作为茜草属植物化学研究的一部分,采用GC/MS对氯仿/甲醇1:1提取物的三萜混合物进行了表征。此外,还对9株临床多重耐药菌株进行了抗菌活性评价。因此,可以考虑作为具有抗菌性能的化合物的来源进行进一步的研究
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PANELFIT-LAWSci-02 Workshop: H2020 Challenges in Law, Technology, Life, and Social Sciences Characterization and overexpression of a glucanase from a newly isolated B. subtilis strain MOL2NET: FROM MOLECULES TO NETWORKS (PROC. BOOK), ISBN: 978-3-03842-820-6, 2019, Vol. 4, 2985 pp. Analysis of chemical composition of Cissus incisa leaves by GC/MS Machine learning techniques and the identification of new potentially active compounds against Leishmania infantum.
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