A pediatric case of resistant lichen planus pigmentosus treated with colchicine

Mehsas Zoubida, Sektaoui Soukaina, Boubnane Ibtissam, Znati Kaoutar, Senouci Karima, B. Laila
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Abstract

This is a case report of a 8-year-old child with lichen planus pigmentosus (LPP), a rare subtype of pediatric lichen planus, successfully treated with colchicine after failure of other therapeutic options. Colchicine was introduced at a dose of 0.5mg/day for 1 year with sun protection, resulting in cessation of the eruption's extension and decrease in hyperpigmentation. No adverse effects were observed. This case highlights the potential of colchicine as a treatment option for pediatric patients with LPP, although further studies with larger sample sizes and longer follow-up periods are needed to establish its safety and effectiveness.
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秋水仙碱治疗顽固性色素扁平苔藓1例
这是一个8岁儿童的病例报告与扁平苔藓色素(LPP),一种罕见的亚型的儿童扁平苔藓,成功地用秋水仙碱治疗失败后,其他治疗方案。以0.5mg/天的剂量引入秋水仙碱,持续1年,并进行防晒,停止了皮疹的延伸,减少了色素沉着。未观察到不良反应。该病例强调了秋水仙碱作为小儿LPP患者的治疗选择的潜力,尽管需要进一步研究更大的样本量和更长的随访期来确定其安全性和有效性。
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