NANOSTRUCTURES FROM DESIGNER PEPTIDES

B. T. Ong, P. K. Ajikumar, S. Valiyaveettil
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Abstract

The present article reviews the self-assembly of oligopeptides to form nanostructures, both in solution and in solid state. The solution structures of the peptides were examined using circular dichroism and dynamic light scattering. The solid state assembly was examined by adsorbing the peptides onto a mica surface and analyzing it using atomic force microscopy. The role of pH and salt concentration on the peptide self-assembly was also examined. Nanostructures within a size range of 3–10 nm were obtained under different conditions.
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设计肽的纳米结构
本文综述了在溶液和固体状态下寡肽自组装形成纳米结构的研究进展。利用圆二色性和动态光散射检测了肽的溶液结构。通过将肽吸附到云母表面并使用原子力显微镜对其进行分析来检测固态组装。还研究了pH和盐浓度对肽自组装的作用。在不同条件下获得了3 ~ 10 nm的纳米结构。
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