Antimicrobial and Anticancer Effect of Bioactive Compounds in Red Beet Roots التأثير المضاد للنشاط الميکروبى و المضاد للسرطان للمواد الفعاله فى جذور البنجر الأحمر.

Samah M. Abd Elraziek, Mona Khalil, A. K. A. El-Hameed, Rania E. El-Gamal
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Abstract

This research was carried out to study the bioactive compounds which found in red beet roots as antimicrobial activity and as anticancers in the lung and breast . Red beet roots were used and a set of technological treatments (drying, blanching than drying and freeze-drying) were carried out to choose the most appropriate treatments to reduce the loss of bioactive substances. Chemical properties, minerals and active substances were estimated for each of the previous treatments.   Results showed that the drying treatment of red beet roots exhibited the lowest rates of loss in chemical composition and active substances.   Methanolic extract of fresh red beet roots and other treatments of red beet roots as antimicrobial activity of some types of bacteria, fungi and yeasts, and the results showed positive effects on bacteria and yeast.   Also, the effect of the methanolic extract of fresh beet roots and other treatment of  red beet roots were examined as anticancers on the carcinogenic cells of the lung and breast.The results showed that the IC50 obtained from fresh and dried red beet roots extract were 352, 227, 242 and 321 µg/ml on both of  breast and lung cancer cells, respectively. Therefore, the study recommends that red beet roots could be added in many foodstuffs to reduce the incidence of cancer.
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微生物和生物生物在红甜菜根活性物质的抗癌作用。
这项研究是为了研究在红甜菜根中发现的具有抗菌活性的生物活性化合物,以及在肺和乳腺中的抗癌活性。以红甜菜根为研究对象,通过对红甜菜根进行干燥、焯水、冷冻干燥等工艺处理,选择最适宜的处理方式,减少其生物活性物质的流失。对每一种处理的化学性质、矿物质和活性物质进行了估计。结果表明,干燥处理红甜菜根的化学成分和活性物质损失率最低。新鲜红甜菜根甲醇提取物和其他处理对红甜菜根的某些细菌、真菌和酵母菌的抑菌活性进行了比较,结果显示出对细菌和酵母菌的积极作用。此外,还研究了新鲜甜菜根的甲醇提取物和红甜菜根的其他处理对肺和乳腺致癌细胞的抗癌作用。结果表明,鲜、干红甜菜根提取物对乳腺癌和肺癌细胞的IC50分别为352、227、242和321µg/ml。因此,该研究建议,可以在许多食品中添加红甜菜根,以减少癌症的发病率。
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