A. Annaházi, T. Berger, I. Demir, F. Zeller, M. Müller, Markus Anneser, A. Skerra, K. Michel, M. Schemann
{"title":"Metabotropic 5‐HT receptor‐mediated effects in the human submucous plexus","authors":"A. Annaházi, T. Berger, I. Demir, F. Zeller, M. Müller, Markus Anneser, A. Skerra, K. Michel, M. Schemann","doi":"10.1111/nmo.14380","DOIUrl":null,"url":null,"abstract":"Serotonin (5‐HT) is an important mediator in the gastrointestinal tract, acting on different neuronal 5‐HT receptors. The ionotropic 5‐HT3 receptor mediates immediate but transient spike discharge in human enteric neurons. We studied the role of the metabotropic 5‐HT1P, 5‐HT4, and 5‐HT7 receptors to activate human submucous neurons.","PeriodicalId":19104,"journal":{"name":"Neurogastroenterology & Motility","volume":"105 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurogastroenterology & Motility","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/nmo.14380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Serotonin (5‐HT) is an important mediator in the gastrointestinal tract, acting on different neuronal 5‐HT receptors. The ionotropic 5‐HT3 receptor mediates immediate but transient spike discharge in human enteric neurons. We studied the role of the metabotropic 5‐HT1P, 5‐HT4, and 5‐HT7 receptors to activate human submucous neurons.
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