Analysis of risk factors for the development of hyperproliferative endometrial processes in women of reproductive age

Abstract

Based on clinical and statistical analysis, a study of the leading etiopathogenetic factors in the development of hyperplastic processes of the endometrium in patients of reproductive age was carried out.The aim of the study: to study the risk factors for hyperplasia and endometrial polyps in women of early reproductive age.Materials and methods. Clinical and statistical analysis of 120 patients of active reproductive age with verified atypical hyperproliferative pathology of the endometrium (hyperplasia and endometrial polyps) was included in the main group. The main group was divided into subgroups: Subgroup I - 45 women with endometrial hyperplasia, Subgroup II - 45 patients with endometrial polyps and Subgroup III - 30 patients with combined endometrial pathology (hyperplasia and endometrial polyps).Results of reseаrсh. The leading risk factors for the development of hyperplastic endometrial processes in women of the examined groups have been identified: aggravated heredity, high frequency of medical abortions, miscarriages and a history of abnormal births. There is a high incidence of gynecological and extragenital diseases, surgical interventions on the uterus and appendages in the examined contingent of women, which contributes to the development of endometrial pathology. It is established that the most common clinical manifestations of endometrial hyperproliferative processes are pain and hemorrhagic syndromes.Conclusions. Risk factors for hyperproliferative pathology of the endometrium in women of reproductive age are the following: burdened heredity (60.8%), concomitant extragenital pathology (57.4%), menstrual disorders (86.7%), impaired reproductive function; burdened gynecological anamnesis: chronic inflammatory processes of the uterus and appendages (45.8%), artificial (74.2%) and spontaneous (22.5%) abortions; intrauterine surgical interventions (26.7%).