Infection in orthopaedics

Robert A.E. Clayton, A. Hamish R.W. Simpson
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Abstract

Infection in bone and joints is a potentially very serious condition. Prompt recognition, appropriate referral and expeditious treatment are essential in order to avoid serious long term sequelae. Acute septic arthritis is an orthopaedic emergency which requires removal of the pus from the joint and intravenous antibiotics. Acute osteomyelitis, if diagnosed early, will usually settle with a course of antibiotics alone (these should be started immediately after obtaining blood cultures). If the diagnosis is delayed, the patient will require surgical drainage. Chronic osteomyelitis is a variable condition unless. If it is causing minimal morbidity it can be treated non-operatively, more commonly, however, it requires surgical treatment to drain the pus and remove the areas of dead bone. In some cases of implant related sepsis, it is possible to retain the prosthesis but in the majority, the implant has to be revised. In general, in patients with orthopaedic infections, wherever possible, it is preferable to obtain a microbiological diagnosis before initiating antibiotic therapy as appropriately targeted antibiotic therapy increases the chances of eradication of infection.

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骨科感染
骨和关节感染是一种潜在的非常严重的疾病。为了避免严重的长期后遗症,及时识别、适当转诊和迅速治疗是必不可少的。急性脓毒性关节炎是一种骨科急症,需要清除关节脓液和静脉注射抗生素。如果早期诊断出急性骨髓炎,通常仅用一个疗程的抗生素即可解决(这些应在获得血培养后立即开始)。如果诊断延迟,患者将需要手术引流。慢性骨髓炎是一种可变的疾病,除非。如果发病率很小,则可以非手术治疗,但更常见的是,需要手术治疗以排出脓液并去除死骨区域。在一些与假体相关的脓毒症病例中,可以保留假体,但在大多数情况下,必须修改假体。一般来说,对于骨科感染患者,在可能的情况下,在开始抗生素治疗之前最好进行微生物学诊断,因为适当的靶向抗生素治疗可以增加根除感染的机会。
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