S. Itoh, Xin Huang, H. Kawakami, M. Komatsu, Y. Ohshiro, S. Fukuzumi
{"title":"An active site model for calcium(II)-containing quinoproteins","authors":"S. Itoh, Xin Huang, H. Kawakami, M. Komatsu, Y. Ohshiro, S. Fukuzumi","doi":"10.1039/C39950002077","DOIUrl":null,"url":null,"abstract":"The Ca2+ complexes of PQQ-2, 9-dimethyl ester and its iminoquinone derivative have been synthesised and the reactivity towards alcohols examined; the oxidising ability of the quinone is significantly enhanced by binding Ca2+ and NH3, both of which are essential for quinoprotein methanol dehydrogenase activation.","PeriodicalId":17282,"journal":{"name":"Journal of The Chemical Society, Chemical Communications","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Chemical Society, Chemical Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/C39950002077","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
The Ca2+ complexes of PQQ-2, 9-dimethyl ester and its iminoquinone derivative have been synthesised and the reactivity towards alcohols examined; the oxidising ability of the quinone is significantly enhanced by binding Ca2+ and NH3, both of which are essential for quinoprotein methanol dehydrogenase activation.