Green Route Synthesis of Copper Oxide Nanoparticles Against MCF-7 Cell Line (Breast Cancer)

A. Rehman, Awais Shahid Minhas
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引用次数: 1

Abstract

Growing nanostructures by green synthesis is an attractive method with a lot of applications, such as antibacterial, anticancer, antifungal and water treatment, etc. Copper oxide nanoparticles have been fabricated using the extract of Aloe Barbandanum, famous with the name of Aloe vera. These nanoparticles are important due to their applications in medical sciences. Structural, optical, compositional, and morphological properties of synthesized nanoparticles were studied and reported here. The phases and crystallite size were determined using X-ray Diffraction and the UV-visb was used to find out the direct bandgap and the absorbance near the visible range. Fourier Transform Infrared Spectroscopy spectra confirmed the presence of a strong band of metal oxide near 606 cm-1. Using Scanning Electron Microscope the average grain size was obtained as small as 60 nm. These fabricated CuO NPs were tested for their possible uses against the MCF-7 cell line (breast cancer cells) and results are presented.
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绿路合成抗乳腺癌MCF-7细胞的氧化铜纳米颗粒
绿色合成纳米结构在抗菌、抗癌、抗真菌和水处理等领域具有广泛的应用前景。氧化铜纳米颗粒是用芦荟提取物制成的,芦荟以芦荟的名字而闻名。这些纳米粒子在医学上的应用非常重要。本文研究并报道了合成纳米颗粒的结构、光学、组成和形态特性。用x射线衍射法测定了材料的物相和晶粒尺寸,用紫外分光光度法测定了材料的直接带隙和近可见光范围的吸光度。傅里叶变换红外光谱证实在606 cm-1附近存在一个强金属氧化物带。扫描电镜下得到的平均晶粒尺寸小至60 nm。我们测试了这些合成的CuO NPs对MCF-7细胞系(乳腺癌细胞)的可能用途,并给出了结果。
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