Acute arterial thrombosis in anticoagulated patient for acute pulmonary thromboembolism

Ana Chelikikj, L. Poposka, Elena Grueva, E. Kandi̇c, Oliver Bushljeti̇kj, Zhan Zi̇mbakov
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Abstract

Acute limb ischemia is rare in patients with venous thromboembolism who already receive anticoagulation treatment. Inflammation is a risk factor for thrombus formation. Patients with active ulcerative colitis, especially at the time of exacerbation, are more prone to thromboembolism, both venous and arterial. The risk for thrombosis is 18% higher, with a higher risk of bleeding. To date, there is no contraindication to any anticoagulant drug in patients with ulcerative colitis. We represent a case of a 73 year - old woman with ulcerative colitis exacerbation, hospitalized initially for pulmonary thromboembolism, that developed acute arterial thrombosis when switched on a novel oral anticoagulant.
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急性肺血栓栓塞抗凝患者的急性动脉血栓形成
急性肢体缺血在已经接受抗凝治疗的静脉血栓栓塞患者中是罕见的。炎症是血栓形成的危险因素。活动性溃疡性结肠炎患者,尤其是在病情加重时,更容易发生静脉和动脉血栓栓塞。血栓形成的风险要高出18%,出血的风险也更高。迄今为止,溃疡性结肠炎患者没有任何抗凝药物的禁忌症。我们报告了一例73岁的溃疡性结肠炎加重的女性,最初因肺血栓栓塞而住院,在使用一种新型口服抗凝剂后发展为急性动脉血栓形成。
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