A prospective cross-sectional study to analyze the effect of transnasal sphenopalatine ganglion block in carcinoma buccal mucosa patients

N. Lamba, Shikha Dhal, Ruchika Makkar, S. Goyal, S. Sarna
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Abstract

Introduction: Cancer pain is known to be one of the Most severe pain anyone in life and is the primary reason for discontinuation of treatment. Sphenopalatine ganglion block (SPGB) can be useful in alleviating pain of carcinoma buccal mucosa. The study aims to analyze the effect of transnasal SPGB in pain management of patients suffering from carcinoma buccal mucosa. Materials and Methods: It was a hospital-based study done on 150 patients with carcinoma buccal mucosa using a prospective cross-sectional study design. To do statistical analysis, paired t-test was used having SPSS software. Results: On visual analogue scale, intensity of pain was found to be notably reduced from 7.42±2.02 to 3.45±1.21 (P < 0.0001), after first sitting. Preprocedure and postprocedure morphine requirement were 90.24 ± 30.24 and 60.42 ± 0.93 mg/day (P > 0.05) At the conclusion of study, the results were found to be statistically significant. Conclusion: Transnasal SPGB is beneficial in improving patient compliance and reducing pain scores and morphine requirement in patients suffering from carcinoma buccal mucosa.
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一项前瞻性横断面研究分析经鼻蝶腭神经节阻滞治疗癌颊黏膜患者的效果
导读:癌症疼痛是生命中最严重的疼痛之一,也是停止治疗的主要原因。蝶腭神经节阻滞(SPGB)可有效缓解癌颊黏膜疼痛。本研究旨在分析经鼻SPGB在口腔黏膜癌患者疼痛治疗中的作用。材料和方法:这是一项基于医院的研究,采用前瞻性横断面研究设计,对150例口腔粘膜癌患者进行了研究。统计分析采用SPSS软件进行配对t检验。结果:在视觉模拟量表上,首次坐位后疼痛强度由7.42±2.02明显降低至3.45±1.21 (P < 0.0001)。术前、术后吗啡需取量分别为90.24±30.24、60.42±0.93 mg/d (P > 0.05)。研究结束时,差异有统计学意义。结论:经鼻SPGB有利于提高患者的依从性,降低颊粘膜癌患者的疼痛评分和吗啡需求。
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