PROBIOTICS AND MANAGEMENT OF AUTISM SPECTRUM DISORDERS

K. Singla, Abhinob Baruah, Shilpa S. Chapadgaonkar
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Abstract

Studies on gut microbiota have revealed surprisingly diverse effects on human immune system and the disturbances in composition of the commensal microorganisms have shown to increase the incidence of diseases. The microorganisms from these metabolites are helpful in the regulation in the host system. This present review focuses on the intricate mechanisms of immune modulation by probiotic microorganisms and the pathways. Gut microbiome is an important modulator of brain functions as well as behaviour. This review specifically deals with the analysis of microbiota of gut in autism spectrum disorders. They are a group of neurological illness which causes difficulty in social behaviour and communication.
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益生菌与自闭症谱系障碍的管理
对肠道菌群的研究揭示了肠道菌群对人体免疫系统的不同影响,而共生微生物组成的紊乱已被证明会增加疾病的发病率。这些代谢物中的微生物对宿主系统的调节有帮助。本文就益生菌免疫调节的复杂机制及其途径作一综述。肠道微生物群是大脑功能和行为的重要调节剂。本文综述了自闭症谱系障碍患者肠道微生物群的分析。它们是一组神经系统疾病,会导致社会行为和沟通困难。
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