Development of great burdock essence compounds

Genomic Medicine, Biomarkers, and Health Sciences Pub Date : 2012-03-01 DOI:10.1016/j.gmbhs.2012.04.016

Ching-Hui Wang , Fu-Yen Chung , Tong-Rong Tsai , Shiu-Ru Lin , Hsueh-Chiao Liu

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引用次数: 2

Abstract

The nanomicelle encapsulating the water-insoluble substances can solubilize in aqueous solution. In this study, we used nanomicelle technology to develop great burdock essence. Black semen oil extracts of Arnebia euchroma and Angelica sinensis, water extract of Arctium lappa, phospholipid, and glycerol were mixed and homogenized in a high-pressure homogenizer. The particle size of great burdock essence was 167.1 ± 0.96 nm. Concentrations of chlorogenic acid, shikonin, and ferulic acid of great burdock essence were 2.300 ± 0.605, 1.484 ± 0.009, and 1.463 ± 0.006 μg/g, respectively. The great burdock essence had nanoparticle-size molecules, which resulted in easy cellular uptake by endocytosis, and main components of three herbs. However, for more information on the health benefits of the great burdock essence, further studies are needed.

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牛蒡精华化合物的开发

包封水不溶性物质的纳米胶束可溶于水溶液。本研究采用纳米胶束技术制备牛蒡精油。在高压均质机中混合匀浆，将赤草、当归黑精液油提取物、牛蒡水提物、磷脂、甘油进行匀浆。大牛蒡精油的粒径为167.1±0.96 nm。绿原酸、紫草素、阿魏酸含量分别为2.300±0.605、1.484±0.009、1.463±0.006 μg/g。牛蒡精华具有纳米颗粒大小的分子，易于细胞内吞吸收，是三种草药的主要成分。然而，关于牛蒡精华的健康益处的更多信息，还需要进一步的研究。

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Genomic Medicine, Biomarkers, and Health Sciences

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