Morphological Pattern of Gestational Trophoblastic Disease in the University of Benin Teaching Hospital, Benin City: A Twenty Year Review (1993 – 2012)

Abstract

Background: Gestational trophoblastic and the mean age was 31.27 ± 7.36 years. GTD was found to be less common at the extremes of reproductive age, with the peak prevalence being in the third and fourth decades. Partial mole was commonest (52.4%), followed by complete mole (25.0%) and choriocarcinoma (19.0%). The ratio of the benign to malignant lesions was 4:1. The uterus was the commonest site of GTD accounting for 83.3% of cases, while 16.6% of cases were distributed among ectopic sites. There was failure to clinically or grossly identify molar vesicles in 80.6% of cases of hydatidiform mole; this highlights the relevance of histopathological examination of products of conception of both intrauterine and ectopic gestation. Conclusion: The prevalence of GTD appears to have been rising in this environment in the recent years.