In Vitro Anticancer Activity of Gamma Oryzanol in Skin Cancer

Abstract

Plants have had an essential role in the folklore of ancient culture. In addition to the use as food and spices, plants have also been utilized as medicines for over 5000 years. Herbal products such as plant extracts, dry powder and parts of plants, fungi, and algae have been used as complementary treatments alongside conventional drugs. Cancer is a severe metabolic syndrome and is one of the leading causes of death regardless of developments in the tools of disease diagnosis, treatment and prevention measures. Cancer is one of the principal causes of mortality and morbidity around the globe and the number of cases are constantly increasing estimated to be 21 million by 2030. Several medicinal plant species and their phytochemicals inhibit the progression and development of cancer. In the present work In vitro anti cancer activity of gamma oryzanol was performed using SRB assay. Result shown that gamma oryzanol has anti cancer activity for SKMEL-2 cancerous cell line. On the basis of this result further study plan can be designed. Key words: Cancer, Gamma oryzanol, Phytochemicals.