Contemporary issues in the management of patient with coronary artery disease across the cardiology spectrum—part II

L. K. Michalis
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Abstract

In the current issue five topics are discussed: a) assessment and management of the cardiovascular risk in patients with chronic kidney disease; b) management of patients with coronary artery disease and chronic kidney disease; c) management of patients with atrial fibrillation and concomitant coronary artery disease; d) the importance of cardiovascular magnetic resonance imaging in patients with ischemic heart disease; and e) stent selection for percutaneous coronary intervention.

Patients with chronic kidney disease are at increased cardiovascular risk due to the coexistance of traditional and kidney disease-related risk factors. Currently, it is presented that the cardiovascular risk assessment and management of the whole spectrum of patients with chronic kidney disease including transplanted and dialysis patients.

Further to this the specific problems of the management of coronary artery disease in patients with established chronic kidney disease are presented. It is known that the mortality risk of the above patients when exhibit coronary artery disease is higher than the average. In addition, their management is a real challenge due to the complexity of anatomy, possibility of acute renal failure, and special considerations, needing to be taken into account when drugs are administered.

Coronary artery disease frequently coexists with atrial fibrillation. When these two conditions have to be managed together, ways of balancing the needs for antiothrombotic and antiplatelets regimes along with the bleeding risk of the patient have to be found. Also the ways of controlling heart rate in such patients or the heart rhythm restoration present a challenging situation.

Cardiovascular magnetic resonance imaging (CMR) offers a broad assessment of cardiac structure and function. In patients with known or suspected heart disease, CMR applications can provide assessment of left ventricular function, myocardial perfusion, and myocardial viability. Currently, the CMR techniques used to assess patients with known or suspected IHD along with situations in which it can be used are fully addressed.

Finally, clinically relevant information with regards to stenting, which is the backbone of the revascularization procedures, is discussed. Technology is advancing and stent characteristics along with patient and vessel factors should be taken into account for the selection of the proper vessel scaffold.

Finishing, I would like to thank again all the contributors of the current issue and especially Dr Jim Hall and Dr Robert Wright for all their effort.

I hope that all trainees and specialists find the current issue both educative and easy to read. I strongly encourage them to find the time and engage themselves to the CME activities accompanying each paper. I am sure it will help them to refresh their knowledge and hopefully improve their everyday clinical practice.

Dr. Michalis reports personal fees from Bayer, Menarini, Actelion, St Jude Medical, Sanofi, and grants from Medronic, Boehringer-Ingelheim, Elpen, St Jude Medical, Leo Pharmaceutical, Boston Scientific, Unipharma, outside the submitted work.

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冠心病患者管理的当代问题——心脏病学谱系第二部分
在本期杂志中讨论了五个主题:a)慢性肾病患者心血管风险的评估和管理;B)冠心病合并慢性肾病患者的管理;C)房颤合并冠状动脉疾病患者的管理;D)心血管磁共振成像在缺血性心脏病患者中的重要性;e)经皮冠状动脉介入治疗支架的选择。由于传统和肾脏疾病相关危险因素并存,慢性肾脏疾病患者心血管风险增加。目前,对包括移植肾和透析肾患者在内的全谱慢性肾病患者进行心血管风险评估和管理。此外,具体问题的管理冠状动脉疾病的患者确定慢性肾脏疾病提出。已知上述患者出现冠状动脉疾病时的死亡风险高于平均水平。此外,由于解剖结构的复杂性,急性肾功能衰竭的可能性,以及在给药时需要考虑的特殊因素,它们的管理是一个真正的挑战。冠状动脉疾病常与心房颤动共存。当这两种情况必须同时处理时,必须找到平衡抗血栓和抗血小板治疗方案需求以及患者出血风险的方法。此外,控制心率或恢复心律的方法也面临着挑战。心血管磁共振成像(CMR)提供了心脏结构和功能的广泛评估。在已知或疑似心脏病的患者中,CMR应用可以评估左心室功能、心肌灌注和心肌活力。目前,用于评估已知或疑似IHD患者的CMR技术及其可用于的情况已得到充分解决。最后,本文讨论了支架置入术的临床相关信息,支架置入术是血管重建术的支柱。随着技术的进步,在选择合适的血管支架时应考虑支架的特性以及患者和血管的因素。最后,我要再次感谢本期的所有撰稿人,尤其是Jim Hall博士和Robert Wright博士,感谢他们的努力。我希望所有的学员和专家都能发现本期杂志既具有教育意义又易于阅读。我强烈建议他们抽出时间参加每篇论文的CME活动。我相信这将有助于他们更新知识,并有望改善他们的日常临床实践。Michalis报告了拜耳、美纳里尼、Actelion、St Jude Medical、赛诺菲的个人费用,以及Medronic、Boehringer-Ingelheim、Elpen、St Jude Medical、Leo Pharmaceutical、Boston Scientific、Unipharma在提交的工作之外的资助。
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