Effect of Hyperglycemia on Immune Function

D. Chandra
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Abstract

Diabetes Mellitus (DM) is a metabolic disorder which leads to many serious secondary complications like retinopathy, neuropathy, nephropathy, cardiovascular complication, delayed wound healing etc. Diabetics are more prone to infection due to compromised immunity. Hyperglycaemia leads to oxidative and osmotic stress. This short communication is the preliminary study to know the effect of high glucose concentration (mimicking hyperglycemia) and H2O2 (mimicking oxidative stress) on murine macrophage cell line RAW 264.7. Methodology
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高血糖对免疫功能的影响
糖尿病(DM)是一种代谢性疾病,可导致视网膜病变、神经病变、肾病、心血管并发症、伤口愈合延迟等严重的继发性并发症。糖尿病患者由于免疫力低下,更容易感染。高血糖导致氧化和渗透应激。这次简短的交流是了解高葡萄糖(模拟高血糖)和H2O2(模拟氧化应激)对小鼠巨噬细胞系RAW 264.7影响的初步研究。方法
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