Potential Side-Effects of CSC Systemic Approach

Nelli Roosipuu, Alina Vijulie, R. Dolz-Marco, R. Gallego-Pinazo
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Abstract

Central serous chorioretinopathy (CSC) is characterized by the development of serous retinal detachment typically involving the macular area [1,2]. It may be recurrent in 30-50% of cases, leading to significant visual impairment [2]. Its etiopathogenesis remains uncertain, with a variety of genetic and environmental factors possibly involved [1,2]. Among these, the role of steroids has arisen as a potential therapeutic target with the use of mineralocorticoid inhibitors like spironolactone or eplerenone [1,3].
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CSC系统方法的潜在副作用
中枢性浆液性脉络膜视网膜病变(CSC)的特点是发生浆液性视网膜脱离,通常累及黄斑区[1,2]。30-50%的病例可复发,导致严重的视力损害[2]。其发病机制尚不明确,可能涉及多种遗传和环境因素[1,2]。其中,类固醇作为一种潜在的治疗靶点已经出现,可以使用矿物皮质激素抑制剂,如螺内酯或依普利酮[1,3]。
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