Correlation of PCSK9 and Serum sdLDL Levels and Other Demographic and Laboratory Indicators in Healthy Individuals

Reza Hosseini-Fard, M. Khosravi, Azim Shamseddin Beiranvand, S. Taghilou, Meysam Havasimeher, Asghar Mohammadi, Sadegh Piran Kashani, E. Soltanmohammadi
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引用次数: 1

Abstract

Accepted: 15 Apr 2017 Abstract Background and Objectives: Atherosclerosis is a type of cardiovascular disease (CVD), which is known as the most important cause of death in the world. In atherosclerosis, arteries get thicker due to the entry of lipids and become inflamed. Epidemiological studies have shown that in addition to demographic and laboratory factors (age, sex, cholesterol, smoking, hypertension, obesity, and diabetes), genetic factors are also associated with progression of atherosclerosis. LDL-C is one of the most important risk factors for cardiovascular disease. In this study, the relationship of PCSK9 levels with serum sdLDL-C levels and other variables, was investigated.
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健康人群PCSK9与血清sdLDL水平及其他人口统计学和实验室指标的相关性
摘要背景与目的:动脉粥样硬化是一种心血管疾病(CVD),是世界上最重要的死亡原因。在动脉粥样硬化中,动脉因脂质进入而变厚并发炎。流行病学研究表明,除了人口统计学和实验室因素(年龄、性别、胆固醇、吸烟、高血压、肥胖和糖尿病)外,遗传因素也与动脉粥样硬化的进展有关。LDL-C是心血管疾病最重要的危险因素之一。本研究探讨PCSK9水平与血清sdLDL-C水平及其他变量的关系。
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