Reactive Arthritis after BCG Therapy in Bladder Carcinoma

Saajid Anwar, Anoushka Agarwal, P. Velammal, S. Menon
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Abstract

Bladder cancer is a common malignancy in women and is the fourth most common malignancy in men. Bladder cancer ranges from nonaggressive and usually noninvasive tumors that recur and require long-term invasive follow-up to aggressive and invasive tumors with high disease-specific mortality. Bacillus Calmette Guerin (BCG) intravesical immunotherapy, a vaccine derived from attenuated Mycobacterium strains - Bovis is one of the most effective bladder cancer therapies currently available. Reactive arthritis has occurred in between 0.5% and 1% of bladder cancer patients treated with intravesical BCG immunotherapy. Here, we present a 66-year-old man diagnosed with urothelial carcinoma undergoing intravesical BCG therapy with high-grade fever and polyarthralgia.
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卡介苗治疗膀胱癌后反应性关节炎
膀胱癌是女性常见的恶性肿瘤,也是男性第四大常见恶性肿瘤。膀胱癌的范围从复发且需要长期浸润性随访的非侵袭性和通常非侵袭性肿瘤到具有高疾病特异性死亡率的侵袭性和侵袭性肿瘤。卡介苗(Bacillus Calmette Guerin, BCG)膀胱内免疫疗法是一种从牛分枝杆菌(Mycobacterium - Bovis)减毒菌株中提取的疫苗,是目前最有效的膀胱癌治疗方法之一。在接受膀胱内卡介苗免疫治疗的膀胱癌患者中,反应性关节炎发生率在0.5%至1%之间。在此,我们报告一位66岁的男性,诊断为尿路上皮癌,接受膀胱内卡介菌治疗,伴有高热和多关节痛。
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期刊介绍: Indian Association of Clinical Medicine is an academic body constituted in the year 1992 by a group of clinicians with the main aim of reaffirming the importance of clinical medicine in this era of high-tech diagnostic modalities. There is no doubt that modern investigational methods have contributed a lot to the present day medical practice but that does not render clinical acumen and examination less important. The art and science of clinical medicine helps up to make proper and judicious use of investigations and not these be the sole basis of our practice. That is the basic idea behind this ''Association''. We presently have members and fellows of the association from all over the country. In August, 2002 the body was registered as "Indian Association of Clinical Medicine" by the Registrar of Societies, Delhi.
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