Non-surgical approach to a paediatric pilocytic astrocytoma with MRI follow-up. Case report and brief literature review

Q4 Pharmacology, Toxicology and Pharmaceutics Acta Marisiensis - Seria Medica Pub Date : 2022-12-01 DOI:10.2478/amma-2022-0022
Andrei-Cristian Fülöp, Zeno Opriș, Eugen-Francisc Fülöp, Ioana-Geanina Ghilință, Cătălin Andrei Zăgan, Attila Kövecsi
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Abstract

Abstract Introduction: Pilocytic astrocytoma is a common tumour in paediatric patients. A low-grade glioma, it is most commonly treated by surgery, with various post-surgical side effects. New methods of treatment and follow-up are constantly evolving to offer alternative options to paediatric patients whose nerve structures are developing. Case presentation: A 9-year-old patient diagnosed with a pilocytic astrocytoma by MRI and histopathological examination underwent a biopsy and evacuation procedure of the cystic component after which the patient’s condition improved significantly. The ‘wait-and-see’ approach using MRI instead of total surgical excision of the tumour was preferred, and the patient had favourable results on control imaging. Conclusions: Paediatric patients suffering from pilocytic astrocytoma with favourable imaging and histopathological features may consider MRI follow-up instead of surgical excision until the character of the tumour changes or until the brain has reached full development.
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小儿毛细胞星形细胞瘤的非手术治疗及MRI随访。病例报告及简要文献复习
摘要简介:毛细胞星形细胞瘤是儿科常见的肿瘤。这是一种低级别胶质瘤,最常用的治疗方法是手术,手术后有各种副作用。新的治疗和随访方法不断发展,为神经结构正在发育的儿科患者提供替代选择。病例介绍:一名9岁的患者通过MRI和组织病理学检查诊断为毛细胞星形细胞瘤,并进行了活检和囊性成分的清除手术,之后患者的病情明显改善。使用MRI的“观望”方法优于完全手术切除肿瘤,并且患者在对照成像中有良好的结果。结论:具有良好影像学和组织病理学特征的毛细胞星形细胞瘤患儿可考虑MRI随访而非手术切除,直至肿瘤特征改变或脑发育完全。
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来源期刊
Acta Marisiensis - Seria Medica
Acta Marisiensis - Seria Medica Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.40
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0.00%
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0
审稿时长
24 weeks
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