Rhinosinusal Melanomas

Ruggeri Carlos S, F. Eduardo, Lorea Agustina, Gonzalez Gabriel Rondón, Riveros Carolina
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Abstract

Purpose: Melanomas are malignant tumors that have a poor prognosis and surgical treatment is the best option when they are resectable. In this study we determined the incidence and survival what we achieved in our population of patients treated for melanomas of the nasal cavity and paranasal sinuses. Material and methods: The medical records of all patients diagnosed with rhinosinusal malignant tumors at the hospital Italiano of Buenos Aires from March 1999 to December 2020 were reviewed. Patients with melanomas were selected y and we determine its incidence within malignant rhinosinusal tumors. Clinical characteristics, location, type of treatment indicated, and results were analyzed. Results: Eight patients had melanomas, five located in the paranasal sinuses, two in the nasal cavity and one in nasal cavity and maxillary sinus. The incidence of melanomas in our population of patients with rhinosinusal malignant tumors was 11.11%. Three patients were treated with surgery and radiotherapy and three with surgery only. Two were treated with palliative criteria. In the six patients treated with curative intent, the local control and specific survival were 83.33%, and 66.66% respectively. The average follow up time was 30.99 months. Conclusions: The incidence of melanomas in our population of patients with rhinosinusal malignancies was 11.11%. In patients treated with curative intention, the local control rate was 83.33%, and disease-free survival was 66.66%. The more frequently failure pattern was the appearance of distant metastases. Endonasal surgery with endoscopes alone or associated with an external approach facilitated oncological resection.
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目的:黑色素瘤是一种预后较差的恶性肿瘤,在可切除的情况下,手术治疗是最佳选择。在这项研究中,我们确定了鼻腔和鼻窦黑色素瘤患者的发病率和生存率。材料与方法:回顾1999年3月至2020年12月在布宜诺斯艾利斯意大利医院诊断为鼻鼻恶性肿瘤的所有患者的医疗记录。我们选择黑色素瘤患者并确定其在鼻鼻恶性肿瘤中的发病率。分析其临床特点、部位、治疗类型及结果。结果:黑色素瘤8例,5例位于鼻窦,2例位于鼻腔,1例位于鼻腔和上颌窦。黑素瘤在我国鼻鼻恶性肿瘤患者中的发病率为11.11%。3例患者行手术加放疗,3例仅行手术治疗。其中2例采用姑息治疗标准。6例有治愈意向的患者,局部控制率为83.33%,特异性生存率为66.66%。平均随访时间30.99个月。结论:黑素瘤在鼻鼻恶性肿瘤患者中的发病率为11.11%。有治愈意向的患者,局部控制率为83.33%,无病生存率为66.66%。更常见的失败模式是远处转移的出现。鼻内镜手术单独或联合外部入路有利于肿瘤切除。
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