Chun-lei Zhou, Xiangfang Yang, Zhihui Xie, D. Miao, Yong Sun, Bin Shi
{"title":"Investigation of risk factors of coronary artery stenosis in flying personnel","authors":"Chun-lei Zhou, Xiangfang Yang, Zhihui Xie, D. Miao, Yong Sun, Bin Shi","doi":"10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007","DOIUrl":null,"url":null,"abstract":"Objective \nTo investigate the main risk factors induced to coronary artery stenosis in order to provide evidence for prevention of coronary heart disease in flying personnel. \n \n \nMethods \nBy analyzing the computed tomography angiography (CTA), 44 flying personnel clinically suspected as coronary heart disease were divided into coronary artery stenosis group and normal coronary artery group. The comparisons on age, flying aircraft type, flying duties, body mass index (BMI), flying hours, night flying hours, blood lipid level, serum glucose level, histories of hypertension and smoking were conducted between two groups. The Logistic multivariate regression analysis was used for determining risk factors. \n \n \nResults \nThe CTA results indicated 25 cases (56.82%) of coronary artery stenosis and 19 normal cases. The univariate analysis showed the statistical differences on age, flight hours, night flight hours, and the incidences of hypercholesterolemia, hyper low-density lipoprotein cholesterolemia, Hypo high-density lipoprotein cholesterolemia and hypertriglyceridemia between coronary artery stenosis group and coronary artery normal group (χ2=4.429-14.329, P<0.05). The Logistic multivariate regression analysis showed that hyper low-density lipoprotein cholesterolemia (OR=7.026, 95%CI: 1.831-26.959, P<0.05) and night flight hours (OR=4.461, 95%CI: 1.694-11.746, P<0.05) were the independent risk factors of coronary artery stenosis. \n \n \nConclusions \nHyper low-density lipoprotein cholesterolemia and night flying hours are the independent risk factors of coronary artery stenosis in pilots. These hint that the change of circadian rhythms would be an important factor to induce coronary artery stenosis besides the common risk factors. \n \n \nKey words: \nCoronary artery stenosis; Circadian rhythm; Risk factors; Flying personnel","PeriodicalId":9904,"journal":{"name":"中华航空航天医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华航空航天医学杂志","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-6239.2018.03-04.007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To investigate the main risk factors induced to coronary artery stenosis in order to provide evidence for prevention of coronary heart disease in flying personnel.
Methods
By analyzing the computed tomography angiography (CTA), 44 flying personnel clinically suspected as coronary heart disease were divided into coronary artery stenosis group and normal coronary artery group. The comparisons on age, flying aircraft type, flying duties, body mass index (BMI), flying hours, night flying hours, blood lipid level, serum glucose level, histories of hypertension and smoking were conducted between two groups. The Logistic multivariate regression analysis was used for determining risk factors.
Results
The CTA results indicated 25 cases (56.82%) of coronary artery stenosis and 19 normal cases. The univariate analysis showed the statistical differences on age, flight hours, night flight hours, and the incidences of hypercholesterolemia, hyper low-density lipoprotein cholesterolemia, Hypo high-density lipoprotein cholesterolemia and hypertriglyceridemia between coronary artery stenosis group and coronary artery normal group (χ2=4.429-14.329, P<0.05). The Logistic multivariate regression analysis showed that hyper low-density lipoprotein cholesterolemia (OR=7.026, 95%CI: 1.831-26.959, P<0.05) and night flight hours (OR=4.461, 95%CI: 1.694-11.746, P<0.05) were the independent risk factors of coronary artery stenosis.
Conclusions
Hyper low-density lipoprotein cholesterolemia and night flying hours are the independent risk factors of coronary artery stenosis in pilots. These hint that the change of circadian rhythms would be an important factor to induce coronary artery stenosis besides the common risk factors.
Key words:
Coronary artery stenosis; Circadian rhythm; Risk factors; Flying personnel
期刊介绍:
The aim of Chinese Journal of Aerospace Medicine is to combine theory and practice, improve and popularize, actively advocate a hundred flowers bloom and a hundred schools of thought contend, advocate seeking truth from facts, promote the development of the related disciplines of aerospace medicine and human efficiency, and promote the exchange and penetration of aerospace medicine and human efficiency with other biomedical and engineering specialties.
Topics of interest for Chinese Journal of Aerospace Medicine include:
-The content of the journal belongs to the discipline of special medicine and military medicine, with the characteristics of multidisciplinary synthesis and cross-penetration, and mainly reflected in the aerospace industry, aerospace flight safety and efficiency, as well as the synthesis of special medicine, preventive medicine, environmental medicine, psychology, etc.
-Military aeromedicine (Air Force, Navy and Army aeromedicine) and civil aeromedicine, with a balance of aerospace medicine are the strengths of the journal.
-The change in aerospace medicine from a focus on promoting physiological compensatory adaptations to enhancing human performance under extreme environmental conditions is what the journal is helping to promote.
-The expansion of manuscripts in high altitude medicine is also a special emphasis of the journal.