Equity in Genomic Medicine.

IF 7.7 2区生物学 Q1 GENETICS & HEREDITY Annual review of genomics and human genetics Pub Date : 2022-04-01 DOI:10.1146/annurev-genom-112921-022635

C. H. Halbert

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Abstract

Since the completion of the Human Genome Project, considerable progress has been made in translating knowledge about the genetic basis of disease risk and treatment response into clinical services and public health interventions that have greater precision. It is anticipated that more precision approaches to early detection, prevention, and treatment will be developed and will enhance equity in healthcare and outcomes among disparity populations. Reduced access to genomic medicine research, clinical services, and public health interventions has the potential to exacerbate disparities in genomic medicine. The purpose of this article is to describe these challenges to equity in genomic medicine and identify opportunities and future directions for addressing these issues. Efforts are needed to enhance access to genomic medicine research, clinical services, and public health interventions, and additional research that examines the clinical utility of precision medicine among disparity populations should be prioritized to ensure equity in genomic medicine. Expected final online publication date for the Annual Review of Genomics and Human Genetics, Volume 23 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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基因组医学的公平性。

自人类基因组计划完成以来，在将疾病风险和治疗反应的遗传基础知识转化为更精确的临床服务和公共卫生干预措施方面取得了相当大的进展。预计将制定更精确的早期发现、预防和治疗方法，并将加强差距人群在保健和成果方面的公平性。获得基因组医学研究、临床服务和公共卫生干预的机会减少，有可能加剧基因组医学方面的差距。本文的目的是描述基因组医学公平的这些挑战，并确定解决这些问题的机会和未来方向。需要努力加强获得基因组医学研究、临床服务和公共卫生干预措施的机会，并应优先考虑进一步研究精准医学在差异人群中的临床效用，以确保基因组医学的公平性。预计《基因组学与人类遗传学年度评论》第23卷的最终在线出版日期为2022年10月。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual review of genomics and human genetics 生物-遗传学

CiteScore

14.90

自引率

1.10%

发文量

期刊介绍： Since its inception in 2000, the Annual Review of Genomics and Human Genetics has been dedicated to showcasing significant developments in genomics as they pertain to human genetics and the human genome. The journal emphasizes genomic technology, genome structure and function, genetic modification, human variation and population genetics, human evolution, and various aspects of human genetic diseases, including individualized medicine.

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