Comparison of Total Salivary Antioxidants in Smokers and Non-smokers With Chronic Periodontitis

Abstract

Background and Objectives Periodontitis is an inflammatory disease that involves supporting tooth structure, can be affected by risk factors like smoking, and increase the prevalence and severity of periodontal damages. Antioxidant stress to target molecule and prevent from degeneration of normal cells. This study aimed to compare the salivary total antioxidant level in smokers and non-smokers with chronic periodontitis. Subjects and Methods A case-control study was performed in 60 chronic periodontitis patients (30 smokers and 30 non – smokers) in referral patients to Ahvaz Jundishapoor university of Medical Sciences, School of Dentistry. Saliva samples were collected from all subjects and the total salivary antioxidant level in these subjects measured with the spectrophotometry method in 600 nm wavelength. data analyzed with t-test statistical analysis. Results A significant difference between total salivary antioxidant level in smokers and non-Smokers patients with chronic periodontitis observed (P<0.001). Conclusion This study showed decreasing in total salivary antioxidant level in the smoker- patients with chronic periodontitis compared to non-smoker patients with chronic periodontitis.