The way of inductive formation of medical diagnostic knowledge bases

A. Kleschev, S. Smagin
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引用次数: 1

Abstract

The paper provides an introduction into the area of inductive formation of knowledge bases. It presents traditional definitions of main problems in this area and highlights the current topical questions including the interpretability of the results. For solving of current problems in defined area the method of inductive formation of easily interpretable medical diagnostic knowledge bases is suggested. It includes the new definitions of classification and clustering problems for dependence models with parameters and the learning algorithm (solving mentioned problems in their new definitions) developed for the practically useful and easily interpretable mathematical dependence model with parameters which is a near real-life ontology of medical diagnostics (defined by a system of logical relationships with parameters). Also it includes the software package InForMedKB (INductive FORmation of MEDical Knowledge Bases) which implements above mentioned learning algorithm. InForMedKB allows to create training sets (consisting of clinical histories from various therapeutic areas) and to use them for inductive formation of medical diagnostic knowledge bases. These knowledge bases are presented in form accepted in the medical literature and contain descriptions of diseases (from specified therapeutic areas) as well as an explanation of these knowledge bases based on descriptions of clinical histories from used training sets. The formal representation of medical knowledge bases enables their usage for intelligent systems for medical diagnostics.
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医学诊断知识库的归纳形成途径
本文对知识库的归纳形成领域进行了介绍。它提出了该领域主要问题的传统定义,并强调了当前的主题问题,包括结果的可解释性。针对目前在限定区域内存在的问题,提出了归纳形成易解释医学诊断知识库的方法。它包括对参数依赖模型的分类和聚类问题的新定义,以及为具有实际用途且易于解释的具有参数的数学依赖模型(由具有参数的逻辑关系的系统定义)开发的学习算法(解决新定义中提到的问题),该模型是接近现实生活的医学诊断本体(由参数逻辑关系系统定义)。其中还包括实现上述学习算法的软件包InForMedKB (induction FORmation of MEDical Knowledge Bases)。InForMedKB允许创建训练集(由来自不同治疗领域的临床病史组成),并使用它们归纳形成医学诊断知识库。这些知识库以医学文献中可接受的形式呈现,并包含疾病的描述(来自特定的治疗领域),以及基于使用的训练集的临床病史描述对这些知识库的解释。医学知识库的形式化表示使其能够用于医疗诊断的智能系统。
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