Biological Applications of Imidazothiazole Scaffolds: A Current Review

R. Senthil Kumar, Sekar Praveen, Kumar Shridharshini, Murugesan Maruthamuthu, Karthikeyan Mohanapriya, A. Mythili
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引用次数: 2

Abstract

Due to the broad-spectrum biological activities, fused heterocyclic compounds are one of the most important systems in medicinal chemistry. Among them, the imidazothiazole which contains a bridgehead nitrogen atom has a vital role because of various applications such as anticancer, antimalarial, antiviral, etc. Designing various imidazothiazole scaffolds has become more important because of their several biological applications. The present review paper discusses the numerous biological applications of imidazothiazole scaffolds in the field of medicine. The review would be useful in future drug design for the development of more promising drug-like scaffolds.
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咪唑噻唑支架的生物学应用研究进展
由于具有广谱的生物活性,融合杂环化合物是药物化学中最重要的体系之一。其中,含有桥头堡氮原子的咪唑噻唑在抗癌、抗疟、抗病毒等多种应用中具有至关重要的作用。设计各种咪唑噻唑支架由于其多种生物学应用而变得越来越重要。本文综述了咪唑噻唑支架在医学领域的众多生物学应用。该综述将有助于未来药物设计和开发更有前途的类药物支架。
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