{"title":"Hershberger Bioassay in Rats (H assay) (OECD TG 441) (including OECD GD 115 on the Weanling Hershberger Bioassay)","authors":"","doi":"10.1787/9789264304741-21-en","DOIUrl":null,"url":null,"abstract":"671. Modality detected/endpoints: androgens (weights of ventral prostate, seminal vesicles, LABC [levator ani plus bulbocavernosus muscle complex], cowpers glands, glans penis ↑); anti-androgens (weights of testosterone stimulated ventral prostate, seminal vesicles, LABC, cowpers glands, glans penis ↓); optional others (e.g. liver, paired kidney, paired adrenal and testis weights, changes in serum hormones including thyroid hormones). Note: weanling H assay does not include glans penis.","PeriodicalId":19458,"journal":{"name":"OECD Series on Testing and Assessment","volume":"2021 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"OECD Series on Testing and Assessment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1787/9789264304741-21-en","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
671. Modality detected/endpoints: androgens (weights of ventral prostate, seminal vesicles, LABC [levator ani plus bulbocavernosus muscle complex], cowpers glands, glans penis ↑); anti-androgens (weights of testosterone stimulated ventral prostate, seminal vesicles, LABC, cowpers glands, glans penis ↓); optional others (e.g. liver, paired kidney, paired adrenal and testis weights, changes in serum hormones including thyroid hormones). Note: weanling H assay does not include glans penis.
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