Phytochemical Investigation and Antioxidant Activity of Root Extract of Aloe gilbertii Reynolds, from Konso, Southern Ethiopia

Abstract

Aloe gilbertii belonging to the family Aloaceae is used by local people for treatment various disease such as malaria and wound healing. The main purpose of this study was to investigate phytochemicals and antioxidant activity of the Root Extract of Aloe gilbertii Reynolds Phytochemical screening of the CH2Cl2: CH3OH (1:1) extract revealed the presence of flavonoids, anthraquinone, Alkaloids, saponins, phenol and absence of steroids and phytosterols. The anti-oxidant potential and total antioxidant potential was determined by using reducing power determination method and phosphomolybdate method respectively. The antioxidant capacity of methanol, ethanol and ethyl acetate root extracts fractions of Aloe gilbertii were found to be 244.5±0.631, 241.5±0.112 and 106±1.05 mg of ascorbic acid per 10 mg of dry weight of antioxidant in the reducing power, respectively and it’s total antioxidant capacity of these extract fractions were 82.21±0.028, 88.75±0.016 and 74.85±0.043mg of ascorbic acid per 10 mg of dry weight of the crude extract. Thus, the results of the present investigation infer that this plant extracts possess potent antioxidant. Therefore it is strongly recommended to isolate the antioxidant components