[The impact of components of conventional and genetically modified soybeans on parameters of the immune and reproductive systems in female rats].

O. P. Dolaĭchuk, R. Fedoruk, I. Koval'chuk
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Abstract

The article presents results of research of the content of glycoproteins and their specific carbohydrate components, total protein, hemoglobin, erythrocyte, leucocytes molecules of average mass and circulating immune complexes in the blood of female rats under conditions feeding of conventional and transgenic soybeans. Also the reproductive function and mass coefficient of fetus of the studied animals was analyzed. The studies were conducted in three groups of female rats aged 3 months. Animals of I group (control) were kept on a balanced diet during the study period. Animals of groups II and III (research) received a diet according to the scheme of the control group with the addition of 30% from the nutritional value diet native or transgenic soybean, respectively. We found that soy feeding had no significant effect on hematological data in the second and third experimental groups versus control. However, addition to the diet of soybeans, including genetically modified, has a significant impact on the content of glycoproteins and their specific carbohydrate components, female's fertility and less pronounced impact on the data of functional status of their immune system. A generalized analysis of the results of research leads to the conclusion that there is no definite negative or positive impact of GM soy components on their physiological state compared with animals fed native soybeans.
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[传统大豆和转基因大豆成分对雌性大鼠免疫和生殖系统参数的影响]。
本文介绍了饲喂常规和转基因大豆条件下雌性大鼠血液中糖蛋白及其特定碳水化合物组分、总蛋白、血红蛋白、红细胞、白细胞平均质量分子和循环免疫复合物的含量的研究结果。并对所研究动物的生殖功能和胎儿质量系数进行了分析。研究对象为三组3月龄雌性大鼠。ⅰ组(对照组)在研究期间保持均衡饮食。II组和III组(研究)按对照组方案饲喂饲粮,在营养价值饲粮中分别添加30%的天然大豆或转基因大豆。我们发现,与对照组相比,大豆喂养对第二和第三实验组的血液学数据没有显著影响。然而,除大豆外的饮食,包括转基因大豆,对糖蛋白及其特定碳水化合物成分的含量、女性的生育能力有显著影响,对其免疫系统功能状态的数据影响不太明显。对研究结果的综合分析得出结论,与食用天然大豆的动物相比,转基因大豆成分对其生理状态没有明确的负面或正面影响。
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