Incidental bladder wall alteration as a surgical complication risk factor in Indonesian benign prostate hyperplasia patient

Daniel Mahendra Krisna, Akhada Maulana, Erwin Kresnoadi
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Abstract

Bladder obstruction due to benign prostatic hyperplasia (BPH) causes bladder walls alteration such as trabecular and diverticula. Although it is asymptomatic, however it affects the surgery complication. The aim of this study was to evaluate the correlation between bladder wall alteration and post-surgery complications in BPH patients. It was a descriptive observational study with cross-sectional design involving BPH patients who underwent histopathological examination and surgical intervention in the Bhayangkara Hospital Mataram from January 2010-December 2014. Data of the patients including age, place of birth, intraoperative finding, comorbid condition, and post-surgery complication were obtained from the medical record. The relationship between variables was analyzed using Pearson correlation test and linear regression test.A total 114 subjects were involved in this study with the most common age was in the range 60-69 years (43.0%). Seventy-fivesubjects (74.3%) had trans urethra resection of prostate (TURP). Trabecula (28.7%), diverticula (4.0%), and bladder stone (10.9%) were found when the surgical intervention performed. The most common post-surgical complication was chip or clot retention (56.4%). Significantly relationship betweenintraoperative finding with post-surgical complication was observed (r= 0.265; R2 = 0.07; p<0.05). In conclusion, there is correlation between bladder wall alteration and post-surgicalcomplication in BPH patients. Early bladder wall alteration screening is suggested in BPH patients before surgical intervention performed.
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偶然膀胱壁改变是印尼良性前列腺增生患者手术并发症的危险因素
良性前列腺增生(BPH)引起膀胱梗阻,引起膀胱壁改变,如小梁和憩室。虽然无症状,但影响手术并发症。本研究的目的是评估前列腺增生患者膀胱壁改变与术后并发症之间的关系。这是一项横断面设计的描述性观察性研究,涉及2010年1月至2014年12月在马塔兰Bhayangkara医院接受组织病理学检查和手术干预的BPH患者。患者的资料包括年龄、出生地、术中发现、合并症和术后并发症。采用Pearson相关检验和线性回归检验分析变量间的关系。本研究共纳入114名受试者,最常见年龄为60-69岁(43.0%)。75例(74.3%)行经尿道前列腺切除术(TURP)。手术时发现小梁(28.7%)、憩室(4.0%)和膀胱结石(10.9%)。最常见的术后并发症是芯片或血栓潴留(56.4%)。术中发现与术后并发症显著相关(r= 0.265;R2 = 0.07;p < 0.05)。总之,前列腺增生患者膀胱壁改变与术后并发症之间存在相关性。建议BPH患者在手术前进行早期膀胱壁改变筛查。
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