The state of hormonal balance in puberty girls with menstrual function disorders on the background of obesity

Abstract

Menstrual disorders in puberty girls against the background of hormonal imbalance occupy a significant place in the structure of gynecological pathology since in the future, they can lead to stable and irreversible changes in the formation of the reproductive system.The purpose of the work - to study the state of hormonal balance in puberty girls against the background of obesity.Material and methods. 79 adolescent girls with impaired menstrual function on the background of obesity were examined and treated. All subjects were also given a comprehensive examination to determine the level of hormones in the blood serum.Results. It was found that obese adolescent girls have a clear difference in the severity of hyperandrogenic disorders of carbohydrate metabolism and insulin resistance.Conclusion. A clear relationship between the formation of menstrual function and the state of gonadotropic function of the pituitary gland is established. Changes in the hormonal profile of puberty girls were found against the background of obesity, namely hyperleptinemia and leptin resistance, which were corrected by non-drug and drug therapy.