A Pediatric Case Report with Immune Thrombocytopenic Purpura Associated with COVID-19

Abstract

Immune Thrombocytopenic Purpura (ITP) of childhood is identified as isolated thrombocytopenia. While it can be triggered by a viral infection such as hepatitis B, hepatitis C, cytomegalovirus, Epstein-Barr, influenza, herpes, varicella-zoster, and HIV or other immune causes, the reason for ITP remains unknown in most patients. We reported a pediatric case with ITP whose COVID-19 total antibody test was positive. Despite the poor response of high dose intravenous immunoglobulin (IVIG), steroid treatment generated a good result. Our patient had an asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2, SARSCoV-2 infection (COVID-19 infection) and COVID-19 PCR was negative. Since we are in the period of the COVID-19-related pandemic, SARS-CoV-2 should be kept in mind in the etiology of ITP. This case raises awareness of both PCR and antibody screening for COVID-19 in patients with ITP, especially in the pandemic season.