A Novel Hybrid Automaton Framework for Multi-Phase Epidemic Modelling

E. Navarro-López, N. Çabukoglu
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Abstract

A framework for the multi-phase epidemic modelling of SEIARD (Susceptible-Exposed-symptomatic Infectious-Asymptomatic infectious-Recovered by immunity or by vaccination-Dead due to the disease) subpopulations is produced with switching transmission rate, basic reproduction ratio and vaccination strategy. The key novel feature of our model is that we reproduce the different phases of the evolution of the infectious disease by using a hybrid automaton with different discrete locations corresponding to each of the phases of the disease. This is a general modelling framework applicable to the spreading of infectious diseases. We show how the proposed model works with the simulation of different scenarios.
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一种新的多阶段流行病建模混合自动机框架
基于转换传播率、基本繁殖比和疫苗接种策略,建立了SEIARD(易感-暴露-有症状感染-无症状感染-通过免疫或接种恢复-因疾病死亡)亚群的多阶段流行模型框架。该模型的关键新颖之处在于,我们通过使用与疾病的每个阶段对应的具有不同离散位置的混合自动机来再现传染病进化的不同阶段。这是适用于传染病传播的一般建模框架。我们展示了所提出的模型如何与不同场景的模拟一起工作。
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