Can fetal alcohol exposure increase the risk of hypertension? A new study in children and adolescents diagnosed with fetal alcohol spectrum disorder suggests it can.

IF 3.2 3区 医学 Q1 Medicine Alcoholism, clinical and experimental research Pub Date : 2019-10-01 DOI:10.1111/acer.14175
K. Moritz, N. Reid, L. Akison
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引用次数: 1

Abstract

Prenatal alcohol exposure (PAE) is increasingly recognized as being associated with a wide range of physical health problems, in addition to the well-defined neurocognitive difficulties that have been reported (Mattson et al., 2019). In line with other prenatal perturbations, including smoking, inadequate nutrition and exposure to stress, exposure of the fetus to alcohol during critical stages of development may contribute to 'developmental origins of health and disease' (DOHaD), as first proposed by Barker and colleagues (1995). DOHaD suggests that a suboptimal environment in early development may increase susceptibility to conditions such as hypertension, insulin resistance and obesity, which are risk factors for prevalent non-communicable chronic diseases such as cardiovascular disease and type II diabetes (Hanson and Gluckman, 2011). This article is protected by copyright. All rights reserved.
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胎儿酒精暴露会增加患高血压的风险吗?一项针对被诊断为胎儿酒精谱系障碍的儿童和青少年的新研究表明,这是可以的。
产前酒精暴露(PAE)越来越被认为与广泛的身体健康问题有关,除了已报道的定义明确的神经认知困难(Mattson等人,2019)。正如Barker及其同事首次提出的那样(1995年),与其他产前扰动(包括吸烟、营养不足和压力暴露)一样,胎儿在发育的关键阶段接触酒精可能导致"健康和疾病的发育起源" (DOHaD)。DOHaD表明,早期发育的次优环境可能会增加对高血压、胰岛素抵抗和肥胖等疾病的易感性,这些疾病是心血管疾病和II型糖尿病等普遍非传染性慢性疾病的风险因素(Hanson和Gluckman, 2011)。这篇文章受版权保护。版权所有。
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来源期刊
CiteScore
5.90
自引率
9.40%
发文量
219
审稿时长
1 months
期刊介绍: Alcoholism: Clinical and Experimental Research''s scope spans animal and human clinical research, epidemiological, experimental, policy, and historical research relating to any aspect of alcohol abuse, dependence, or alcoholism. This journal uses a multi-disciplinary approach in its scope of alcoholism, its causes, clinical and animal effect, consequences, patterns, treatments and recovery, predictors and prevention.
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