Primary Tuberculous Mastitis

R. Laila, S. Banu, J. Raihan
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Abstract

Background: Tuberculous mastitis is a rare entity in patients with mammary diseaseeven in countries where incidence of tuberculosis is high. In Bangladesh, TB is anendemic disease but breast tuberculosis is rarely reported. Its clinical patterns andtreatment strategies are changing day by day. Objective: To analyze the clinical presentations , diagnosis and treatment of tuberculousmastitis Methods: This is a prospective nonrandomized descriptive study to analyze clinicalpresentations, diagnosis and treatment of hundred (100) cases received care for tuberculousmastitis at the Chest Disease Hospital, Rajshahi, from July' 2012 to July' 2016.Diagnosis was made in all patients by cytological examination from suspected lesions,which revealed typical tuberculous lesions. Patient with some atypical presentationsand doubts in the diagnosis needed histopathological examination and Gene x-pert testto exclude idiopathic granulomatous mastitis and concomitant malignancy. Results: Most of the patients were within reproductive age. The disease affecting theright breast in fifty six patients (56%), left breast in forty three patients (43%) andbilateral in one patient (1%). Palpable lump were present in eighteen patients (18%),chronic discharging sinus with or without lump in thirty four (34%) and breast abscesswith or without discharging sinus in eighteen patients (18%),recent abscess drainagescar with lump in thirty patients(30).Medical therapy with anti-tubercular drugs ranging from 9 to 12 months with follow upmonthly was the mainstay of treatment. Surgical intervention reserved for selectedrefractory cases. Extension of anti-tubercular therapy from 9 to 12 or 18 monthsrequired in fifty-eight(58) patients on the basis of slow clinical response. Completeresolution obtained in 92 patients but residual tiny mass in eight patients confirmed byrepeated FNAC to be fibrotic. Conclusion: Treatment is simple but high index of suspicion is the cornerstone fordiagnosis. Journal of Surgical Sciences (2017) Vol. 21 (1) :19-23
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原发性结核性乳腺炎
背景:结核性乳腺炎是一种罕见的乳房疾病,即使在结核病发病率高的国家也是如此。在孟加拉国,结核病是一种地方病,但乳腺癌很少报道。它的临床模式和治疗策略每天都在变化。目的:分析结核性乳房炎的临床表现、诊断和治疗方法:这是一项前瞻性非随机描述性研究,分析2012年7月至2016年7月在Rajshahi胸病医院接受治疗的100例结核性乳房炎患者的临床表现、诊断和治疗。所有患者均通过疑似病变的细胞学检查诊断,发现典型的结核性病变。患者有一些不典型的表现和对诊断的怀疑,需要进行组织病理学检查和基因x-pert检查,以排除特发性肉芽肿性乳腺炎和伴随的恶性肿瘤。结果:患者以育龄者居多。右乳56例(56%),左乳43例(43%),双乳1例(1%)。可触及肿块18例(18%),有或无肿块的慢性排出性鼻窦34例(34%),有或无排出性鼻窦的乳腺脓肿18例(18%),近期脓肿引流性脓肿伴肿块30例(30)。抗结核药物治疗9至12个月,每月随访是主要治疗方法。手术干预保留用于选定的难治性病例。58例临床反应缓慢的患者需要延长抗结核治疗时间,从9个月延长至12个月或18个月。92例患者获得完全溶解,但8例患者经重复FNAC证实为纤维化。结论:治疗方法简单,但高怀疑指数是诊断的基础。外科杂志(2017)Vol. 21 (1):19-23
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