{"title":"Synthesis and Properties of Oligodeoxynucleotides Carrying 2-Aminopurine","authors":"C. Fàbrega, S. Grijalvo, R. Eritja","doi":"10.2174/1874095201105010001","DOIUrl":null,"url":null,"abstract":"The use of benzoyl, isobutyryl and dimethylaminomethylidene groups for the protection of the exocyclic amino function of 2-aminopurine during oligonucleotide synthesis has been investigated. Best results in the synthesis were ob- tained with the monomers of 2-aminopurine protected with the isobutyryl group.","PeriodicalId":23020,"journal":{"name":"The Open Organic Chemistry Journal","volume":"64 1","pages":"1-8"},"PeriodicalIF":0.0000,"publicationDate":"2011-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Organic Chemistry Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874095201105010001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The use of benzoyl, isobutyryl and dimethylaminomethylidene groups for the protection of the exocyclic amino function of 2-aminopurine during oligonucleotide synthesis has been investigated. Best results in the synthesis were ob- tained with the monomers of 2-aminopurine protected with the isobutyryl group.
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