Local abscess due to BCGitis

Abstract

An eight-month-old girl was brought in because of increasing swelling in the area where the BCG vaccine was given. It was learned that the BCG vaccine was administered at the age of two months. Over time, there was swelling in the vaccination area and gradually increased. There was no consanguinity be-tween mother and father. A sibling of the mother was lost at the age of one, for unknown reasons. The patient’s body tem-perature was normal. On examination, redness and fluctuating swelling with a diameter of about 3 cm was observed in the left deltoid region, where BCG vaccination was administered. Other physical examination findings of the patient were normal. The abscess drained spontaneously shortly after examination. Mycobacterium tuberculosis complex PCR was positive in the drainage material. The strain evaluated to be Mycobacterium bovis from the BCG vaccine was susceptible to isoniazid and rifampin. Lymphocyte subgroups, lymphocyte activation response, burst test and IL-12rβ1 expression were normal in the child with low serum IgG and IgM levels in immunologi-cal tests. Genetic study was planned in terms of other immu-nodeficiencies that predispose to mycobacterial diseases. The patient was started on isoniazid and rifampin treatment. The lesion of the patient, whose treatment was