Chemically Crosslinked Polyvinyl Alcohol/ Gelatin Wound Dressing Loaded With Curcumin

Abstract

Wound dressings are highly desired for the treatment of chronic wound infections. This study aimed to prepare membranes composed of chemically crosslinkedPVA and Gelatin polymers. Curcumin was added to improve the membrane's biological properties. FTIR spectroscopy was used to investigate their chemical structures, while SEM and TGA analysis were applied to studies the morphology of the membrane and the thermal properties of the crosslinked membranes. In addition, the contact angle measurement was also performed to get more information about the physicochemical properties. In addition, the biodegradability studies were performed and the findings highlighted that the prepared biodegradable PVA/ Gelatin/ Curcumin membranes could be efficiently used as dressers for enhancing wound healing.