Sensibilización central al dolor en pacientes con síndrome del latigazo cervical: una revisión

Diego Serrano-Muñoz , Julio Gómez-Soriano , Gerardo Ávila-Martín , Iriana Galán-Arriero , Luis María Romero-Muñoz , Julian S. Taylor , Andrés Barriga-Martín
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引用次数: 4

Abstract

The cervical whiplash syndrome is a disorder that affects a many people following road traffic accidents and which has a high economic cost. The disorders associated with whiplash syndrome are numerous, and include neck pain and muscle stiffness, headache, and dizziness. In approximately 50% of people who suffer from whiplash, the initial pain develops and is maintained into the chronic phase. Mechanisms of central sensitization to pain has been recognized as an important pathophysiological mechanism which may mediate various types of pain and which may be responsible for its chronification in these patients, as they show signs of hypersensitivity to pain, including decreased pain pressure thresholds and altered temporal summation to noxious stimuli. With regards to treatment, although there is a wide range of physical therapies available to treat whiplash disorders, currently there is no consensus on which therapy is most effective. Understanding the mechanisms by which pain becomes chronic following whiplash will help to develop an effective therapy that could directly treat the disorders associated with this pathology in many people with chronic pain symptomatology based on the evidence-based diagnosis of pathophysiological mechanisms.

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颈鞭综合征患者的中枢疼痛敏化:综述
颈椎鞭打综合征是一种影响许多人在道路交通事故后的疾病,具有很高的经济成本。与鞭打综合征相关的疾病有很多,包括颈部疼痛和肌肉僵硬、头痛和头晕。在大约50%的遭受鞭打的人,最初的疼痛发展并维持到慢性阶段。中枢对疼痛的敏感化机制已被认为是一种重要的病理生理机制,它可能介导各种类型的疼痛,并可能导致这些患者的慢性化,因为他们表现出对疼痛超敏感的迹象,包括疼痛压力阈值降低和对有害刺激的时间累积改变。在治疗方面,虽然有多种物理疗法可用于治疗鞭扭伤,但目前对于哪种疗法最有效尚无共识。了解鞭打后疼痛变为慢性的机制将有助于开发一种有效的治疗方法,可以直接治疗许多基于循证病理生理机制诊断的慢性疼痛症状患者与该病理相关的疾病。
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