{"title":"The novel siRNA inclisiran and population health management","authors":"L. Walker","doi":"10.1002/psb.2037","DOIUrl":null,"url":null,"abstract":"Inclisiran (Leqvio) is a first‐in‐class cholesterol‐lowering small interfering RNA (siRNA) that works through gene silencing. Even though it has been approved by NICE and a population health agreement is in place, uptake in general practice has been slow. This article examines the barriers to uptake and how these could be addressed.","PeriodicalId":88184,"journal":{"name":"The Prescriber","volume":"120 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/psb.2037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Inclisiran (Leqvio) is a first‐in‐class cholesterol‐lowering small interfering RNA (siRNA) that works through gene silencing. Even though it has been approved by NICE and a population health agreement is in place, uptake in general practice has been slow. This article examines the barriers to uptake and how these could be addressed.